Publications

Complete list of publications can be found on my Google Scholar page.

Gettler K, Nagpal S, Washburn S, et al. Post-operative ileum transcriptomics implicates sex-biased mechanisms of Crohn's disease recurrence. Gastroenterology.
Nagpal S, Hooshmand K, et al. A genome-wide association study implicates the glutamate signaling pathway in sarcoma susceptibility. (Manuscript submitted).
Graaf VD A, Warmerdam R, Auwerx C, Vosa U, Borges MC, Franke L, Kutalik Z, eQTLGen Consortium. MR-link-2: pleiotropy-robust cis Mendelian randomization validated in three independent reference datasets of causality. Nature Communications.
Freimann K, Brümmer A, Warmerdam R, Rupall TS, Hernández-Ledesma AL, Chiou J, Holzinger ER, Maranville JC, Nakic N, Ongen H, Stefanucci L, Turchin MC, eQTLGen Consortium, et al. Trans-eQTL mapping prioritises USP18 as a negative regulator of interferon response at a lupus risk locus. Nature Communications.

Nagpal S, Gibson G. Dual exposure-by-polygenic score interactions highlight disparities across social groups in the proportion needed to benefit. medRxiv (Manuscript submitted).
Brown M, Dodd A, Shi F, Greenwood E, Nagpal S, et al. Concordant B and T cell heterogeneity inferred from the multiomic landscape of peripheral blood mononuclear cells in a Crohn's disease cohort. Journal of Crohn's and Colitis.

Astore C, Sharma S, Nagpal S, IBD Genetics Consortium, et al. The role of admixture in rare variant contributions to inflammatory bowel disease. Genome Medicine.

Astore C, Nagpal S, Gibson G. Mendelian randomization indicates a causal role for omega-3 fatty acids in inflammatory bowel disease. International Journal of Molecular Sciences.
Nagpal S, Tandon R, Gibson G. Canalization of the polygenic risk of common diseases and traits in the UK Biobank. Molecular Biology and Evolution.

Mo A*, Nagpal S*, Gettler K, et al. Stratification of risk of progression to colectomy in ulcerative colitis via measured and predicted gene expression. American Journal of Human Genetics. (*Equal contribution)
Somenini H, Nagpal S, Venkatesqaran S, et al. Whole-genome sequencing of African Americans implicates differential genetic architecture in inflammatory bowel disease. American Journal of Human Genetics.
Stevens J, Kolachala V, Joshi G, Nagpal S, et al. Angiotensin-converting enzyme-2 (ACE2) expression in pediatric liver disease. Journal of Pediatric Gastroenterology and Nutrition.

Pinese M, Lacaze P, Rath EM, Stone A, Brion MJ, Ameur A, Nagpal S, et al. The Medical Genome Reference Bank contains whole-genome and phenotype data of 2,570 healthy elderly. Nature Communications.

Nagpal S*, Meng X*, Epstein MP, et al. TIGAR: An improved Bayesian tool for transcriptomic data imputation enhances gene mapping of complex traits. American Journal of Human Genetics. (*Equal contribution)

Nagpal S, Gibson G, Marigorta UM. Pervasive modulation of obesity risk by the environment and genomic background. Genes (Basel).